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About the author Philip Short BSc (Maths) CFA Fund Manager Philip is a Fund Manager of Flagships global funds and brings specialist macroeconomic expertise

Patients who approach it with realistic expectations and adequate preparation fare better than those who expect immediate dramatic results

Clinical studies show impressive results, with people losing an average of 13% of their body weight over about 14 months

10.1126/science.1172545 [DOI] [PubMed] [Google Scholar] Ryan L, Hatfield C, Hofstetter M (2002) Caffeine reduces time-of-day effects on memory performance in older adults

So, part of the slow digestion strategy to sustain GLP-1 secretion is dietary fiber to slow down the digestion of nutrients

Mild constipation or changes in appetite for specific foods are reported by many patients but tend to stabilize once your system adapts